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pentobarbital will lessen the extent or impact of fedratinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Outcome of coadministering a robust CYP3A4 inducer with fedratinib hasn't been studied.buprenorphine subdermal implant and pentobarbital both of those improve sedation. Stay clear of or Use A